Training Program in Microbial Pathogenesis and Genomics

Training Sites

  • University of Pennsylvania
  • Children's Hospital of Philadelphia

Our growing community of microbiologists has developed an outstanding environment for mentoring pre- and postdoctoral trainees in prokaryotic biology and genomics. This effort is now producing highly qualified individuals to meet national and international priorities related to bacteriology and bacterial genomics. The training program supports four PhD candidate predoctoral fellows as well as one postdoctoral fellow per year, enabling them to obtain an in-depth experience in any one of 13 laboratories directed by principle investigators who study important aspects of bacterial physiology and genomics or human diseases. The trainers have been selected because their research programs in these areas are well established, being supported by NIH or other federal grants and/or having published extensively on these topics. One of the strengths of the prokaryotic community is a diversity that has already fostered productive scientific interactions between three Schools, six Departments, as well as CHOP at this leading research university. The group of trainers encompasses the major areas of research on bacteria including bacterial-host interactions of leading extracellular and intracellular pathogens, immunopathogenesis and use of bacteria as agents in immunotherapy, the structure and function of key components bacterial cell surface , bacterial signaling of target cells, and human microbiome studies. Our research in progress meetings and seminars within the microbiology program have helped spur the rapid growth of exciting, collaborative work in bacterial pathogenesis, microbial immunopathogenesis, and bacterial metagenomics, with institutional support for deep-sequencing facilities, bioinformatics, and a germ-free mouse core playing important roles in these efforts.
To be trainees on this grant, students must be admitted to candidacy for the PhD degree through the biomedical graduate studies program at the University of Pennsylvania. Inquiries and requests for application forms can be sent to:

240 John Morgan Building
37th & Hamilton Walk
Philadelphia, PA 19104-6064
Telephone: (215) 898-1030
FAX: (215) 898-2671


Training is centered around a research program conducted in the laboratory of one of the trainers whose research interests can be found on our Faculty page. Microbial pathogenesis and genomics related training is supplemented by a number of seminar series, conferences, and retreats organized by the University of Pennsylvania and The Wistar Institute. Fellows also receive training in ethical and responsible conduct in research.


  • Dustin Brisson, PhD, University of Pennsylvania
  • Frederic Bushman, PhD, University of Pennsylvania
  • Igor Brodsky, PhD, University of Pennsylvania
  • Ronald Collman, MD, University of Pennsylvania
  • Fevzi Daldal, University of Pennsylvania
  • Rahul Kohli, MD, PhD, University of Pennsylvania
  • Mark Goulian, PhD, University of Pennsylvania
  • Elizabeth Grice, PhD, University of Pennsylvania
  • Mechthild Pohlschr√∂der, University of Pennsylvania
  • Sunny Shin, PhD, University of Pennsylvania
  • Joseph St. Geme, MD, University of Pennsylvania
  • Gary Wu, MD, University of Pennsylvania
  • Jun Zhu, University of Pennsylvania

Interested candidates should send curriculum vitae and three letters of reference to:

Dr. Jay Zhu
University of Pennsylvania School of Medicine
Department of Microbiology
Room 211B Johnson Pavilion/6076
3610 Hamilton Walk
Philadelphia, PA 19104
Tel (215) 573-4104