Guerraty Laboratory | Cardiovascular Institute | Perelman School of Medicine at the University of Pennsylvania

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Marie A. Guerraty, M.D., Ph.D.

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Assistant Professor of Medicine
2b Division of Cardiovascular Medicine
26 Perelman School of Medicine

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Phone: 215-285-1722
83 Email: marie.guerraty@pennmedicine.upenn.edu

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Admin: Emily Romick
79 Email: Emily.Romick@Pennmedicine.upenn.edu

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Description of Clinical Expertise

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Cardiac imaging, cardiac PET, myocardial blood flow, transthoracic echocardiography, ischemic heart disease, coronary artery disease, coronary microvascular disease

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Description of Research Expertise

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Ischemic heart disease, vascular biology, coronary artery disease, vascular biology, coronary microvascular disease, nuclear cardiology, Perfusion PET, small animal cardiac imaging, functional genomics, transcriptional regulation, FOG2, ZFPM2, TWIST1

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Selected Publications

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Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V Schneider, Delfin G Buyco, Chelsea Lin, Blanca E Himes, Clementina A Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E Furth, Jeffrey T Billheimer, Nicholas J Hand, David E Kaplan, Kyong-Mi Chang, Philip S Tsao, Julie A Lynch, Joseph L Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C Phillips, Daniel J Rader, Rotonya M Carr: A Missense Variant in Human Perilipin 2 (Plin2 Ser251pro) Reduces Hepatic Steatosis In Mice. JHEP Reports Oct 2023 Notes: in press.
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10c Lindsay C Johnson, Marie A Guerraty, Stephen C Moore, Scott D Metzler: Determining the effect of cardiac blood volume on accuracy of uptake rate constants by simulation. Phys Med Biol 68(20): 10.1088/1361-6560/ace0f1, Oct 4 2023.
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166 Pankhuri Singhal, Lindsay Guare, Colleen Morse, DPT, Anastasia Lucas, Marta Byrska-Bishop, Marie A. Guerraty, Dokyoon Kim, Marylyn D. Ritchie, Anurag Verma: DETECT: Feature extraction method for disease trajectory modeling in electronic health records. AMIA Joint Summits on Transl Sci Proc 16(2023): 487-496, Jun 2023.
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103 Wenjian Lv, Apoorva Babu, Michael P. Morley, Kirin Musunuru, Marie Guerraty: A Resource of Gene Expression Data from a Multiethnic Population Cohort of Induced Pluripotent Cell–Derived Cardiomyocytes. Biorxiv May 2023.
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c5 Sharavana Gurunathan, Marie Guerraty: Translational Insights in Coronary Microvascular Disease. J Am Coll Cardiol Basic Trans Science 8(5): 515-517, May 2023.
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184 Guerraty MA, Verma Shefali, Ko YA, McQuillan MA, Conlon D, Tobias JW, Levin MG, Haury W, Zhang C, Judy R, Regeneron Genomics Center, PennMedicine Biobank, Tishkoff S, Damrauer SM, Arany Z, Rader DJ: FOG2 coding variant Ser657Gly is associated with Coronary Microvascular Disease through altered hypoxia-mediated gene transcription. MedRxiv May 2023.
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164 JM Ortega-Legaspi, M Molina, J Leon, A Cunningham, M Guerraty, E Peyster, H Julien, R McLean, L Goldberg, P Bravo: Coronary Flow Reserve is an Independent Predictor of Major Adverse Cardiovascular Events in Long Term Heart Transplantation Survivors. The Journal of Heart and Lung Transplantation 42(4): S78, Apr 2023.
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bc Marie Guerraty, Zoltan Arany: A call for a unified view of coronary microvascular disease. Trends in Cardiovascular Medicine 1738(23): 1-4, Jan 2023.
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17b Shefali Verma, Lindsay Guare, Brett Irving, Michael Levin, Marie A Guerraty: Stratifying Coronary Artery Disease (CAD) GWAS Loci Using Cardiac Perfusion Positron Emission Tomography to Identify Loci for Coronary Microvascular Disease. American Heart Association (AHA) Scientific Sessions 2022, Chicago, IL Nov 2022 Notes: oral presentation.
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183 Shefali Verma, Lindsay Guare, Brett Irving, Regeneron Genetics Cntr, PennMedicine BioBank, Michael Levin, Marie A Guerraty: Genome Wide Association Study of Coronary Microvascular Disease Assessed by Cardiac Perfusion Positron Emission Tomography. American Heart Association (AHA) Scientific Sessions, Chicago, IL Oct 2022 Notes: poster presentation.

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